Alveon introduces S2Dx, the suite that brings the LIMS, the slide viewer and the WSI PACS onto a single foundation : S2Dx LIMS, S2Dx View and S2Dx PACS WSI. An unbroken pre-analytical → diagnosis → archiving chain, with HL7 FHIR SDC structured reports, interoperable and built on international standards.
The LIMS, the WSI viewer and the WSI PACS share one patient master record, one audit log and the same connectors. No brittle middleware : one datum, one truth, one trace.
LIMS · Laboratory information system
The engine of the pathology laboratory : cases, specimens, blocks, slides and the full workflow.
Viewer · WSI
Fluid whole-slide viewing (MRXS, SVS, NDPI…) wired straight to the case, with telepathology built in.
WSI PACS · Image archiving
Whole-slide image storage and delivery through a DICOMweb façade configurable per laboratory.
From the specimen received to the signed report, S2Dx logs the entire journey. A tamper-proof audit trail, digital signatures and append-only archiving that meet ISO 15189 requirements and the French HDS framework.
Who, what, when, from which workstation — every action is recorded and legally defensible.
ISO/HDS logs reject any update or deletion — integrity enforced by database triggers.
Report sign-off with a qualified electronic signature (eIDAS / French RGS**) and cryptographic sealing.
Transport, receipt, fixation, processing — time bounds enforced, non-conformity alerts raised.
sha-256:9f2a…c41e
S2Dx builds on the HL7 FHIR SDC profile (Structured Data Capture) :
the report form is a published Questionnaire, the pathologist's entry a
QuestionnaireResponse. Data is born coded — it never has to be re-keyed,
nor re-interpreted downstream.
ICCR protocols, Bethesda / TBSRTC, national datasets : the Questionnaire validated outside the LIMS is authoritative — no rewriting, no version drift.
Dictation and pre-population feed the structured fields, under the pathologist's review. Every item keeps its before → after history, named and timestamped.
The $extract and $project operations turn the response into a FHIR DiagnosticReport, a CDA R2 document conforming to the IHE PaLM APSR profile (and the French CI-SIS CR-ACP volume) or HL7 v2 OBX segments — entered once, available in every format.
At sign-off the digest of the assembled report is frozen. The signed document and the coded data that produced it stay inseparable and legally defensible.
The direct payoff : data usable with no reprocessing for the tumour board, cancer registries, quality management and clinical research.
S2Dx natively speaks the standards of hospital information systems and national health platforms. Your reports, patient identities and images travel securely, with no re-keying.
Patient, observation & diagnostic resources.
Questionnaire / QuestionnaireResponse, $extract.
HIS messaging & structured documents.
WADO / QIDO / STOW for whole-slide imaging.
LTW (LAB-4) and LAW (LAB-23) profiles & APSR structured report.
CR-ACP volume — Schematron checked on every build.
ICD-11, ICD-O, SNOMED CT, LOINC & CCAM.
Custom integration & webhooks.
Context-aware launch from the EHR — the OAuth2 / OIDC foundation and FHIR R4 server are already in place.
A complete functional scope, from the specimen pot to the signed report, with no third-party software to stack up.
Configurable workflows, decision trees, accreditation checkpoints, from pre-analytical to archiving.
National patient identifier (INS in France), specimens, blocks, slides — one master record shared across the platform.
Per-field visibility and mandatory rules, grossing bench station & dictated descriptions.
Antibody catalogue, technical protocols, analyser worklist & typed results.
Real-time Whisper transcription and a voice assistant built into the report.
LLM-based drafting help, summarisation and suggestions, under the pathologist's control.
Whole slides, patient priors, live co-viewing and second-opinion requests.
Non-conformities, reagents, staff competency & supervised co-signature.
Configurable pathologist cockpit, WSI PACS console, S2Dx Notify alerts.
Keycloak authentication (OIDC/JWT), fine-grained permissions, data purge & consent withdrawal.
Imported ICCR / Bethesda forms, coded entry item by item, extraction to DiagnosticReport, CDA R2 and HL7 OBX.
Documented FHIR R4 API (CapabilityStatement), OAuth2 / OIDC, webhooks — plus SMART on FHIR context-aware launch Coming soon
Structuring the report is not just about writing it faster. It is what makes the data reusable : for the tumour board, for research, and for an AI that proposes without ever deciding on its own.
Dictation and transcription become proposed values for structured fields — never an automatic write to the case.
What must be deterministic does not go through a model : scores are computed by frozen formulas.
A free-text report ends up in a PDF. A structured report stays usable.
The case reaches the meeting documented, and the report's elements are already usable.
A pathology LIMS does not have one pathway, it has as many as it has workstreams. Each has its own set of steps, its own quality controls and its own traceability points — the foundation is shared, the journey is specific.
Registration & patient identity checks
Description & cassetting
Embedding, microtomy, H&E staining
Slide → S2Dx WSI PACS
Reading in S2Dx View & SDC entry
Qualified signature & archiving
Specimen type, medium & critical delay
Centrifugation, filtration
Slides, fixation & staining
Cytotechnologist review
Pathologist · Bethesda / Paris system
Report & screening double reading
Material adequacy check
Tumour enrichment
DNA / RNA & quality control
Technical run / NGS
Variant calling & annotation
Sign-off & report signature
Legal framework verification
Initial findings
In situ examination
Sampling & weights
Additional sampling
Final report & post-mortem review
S2Dx also covers flow cytometry and frozen sections, whose timed intra-operative circuit follows a dedicated pathway. Each workstream is enabled per laboratory.
S2Dx does not bolt compliance on afterwards : it is written into the architecture. Traceability, document quality and data security are native.
Pathology laboratories
Medical devices — quality
At a certified host, before go-live
Data protection